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Phenylbutazone-d9
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):464698
  • cas:1189479-75-1
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 464698
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg;
CAS編號(hào) 1189479-75-1
純度 >98%%
是否進(jìn)口

Description: Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 μM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 μM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-induced acute synovitis. Formulations containing phenylbutazone have been used in the treatment of lameness in horses.

Name: Phenylbutazone-d9
CAS#: 1189479-75-1
Chemical Formula: C19H11D9N2O2
Exact Mass: 317.209
Molecular Weight: 317.4359
Elemental Analysis: C, 71.89; H, 9.20; N, 8.83; O, 10.08

Synonym: Phenylbutazone-d9; Phenylbutazone d9;

IUPAC/Chemical Name: 4-(butyl-d9)-1,2-diphenylpyrazolidine-3,5-dione

InChi Key: VYMDGNCVAMGZFE-ABVHXWLASA-N

InChi Code: InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3/i1D3,2D2,3D2,14D2

SMILES Code: O=C1C(C(N(N1C2=CC=CC=C2)C3=CC=CC=C3)=O)C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001